Publications

（* means equal contribution. For a full list of publications, please go to Google Scholar)

2022

Alcohol consumption, blood DNA methylation and breast cancer: a Mendelian randomisation study.
Xuan Zhou, Lili Yu, Lijuan Wang, Jiarui Xiao, Jing Sun, Yajing Zhou, Xiaolin Xu, Wanghong Xu, Athina Spiliopoulou, Maria Timofeeva, Xiaomeng Zhang, Yazhou He, Haomin Yang, Harry Campbell, Ben Zhang, Yimin Zhu, Evropi Theodoratou, Xue Li.
European Journal of Epidemiology, 2022 [bib]

A systematic review of microbial markers for risk prediction of colorectal neoplasia.
Lili Yu, Gang Zhao, Lijuan Wang, Xuan Zhou, Jing Sun, Xinxuan Li, Yingshuang Zhu, Yazhou He, Kleovoulos Kofonikolas, Debby Bogaert, Malcolm G. Dunlop, Yimin Zhu, Evropi Theodoratou, Xue Li.
British journal of cancer, 2022 [bib]

Association of plasma uric acid levels with cognitive function among non-hyperuricemia adults: A prospective study.
Yuhui Huang, Shen Zhang, Jiadong Shen, Jiaxi Yang, Xiao Chen, Wanlu Li, Jiawen Wang, Xiaolin Xu, Xin Xu, Zuyun Liu, Xue Li, Yanan Ma, Changzheng Yuan.
Clinical nutrition，2022 [bib]

Genetically predicted sex hormone levels and health outcomes: phenome-wide Mendelian randomization investigation.
Shuai Yuan, Lijuan Wang, Jing Sun, Lili Yu, Xuan Zhou, Jie Yang, Yimin Zhu, Dipender Gill, Stephen Burgess, Joshua C. Denny, Susanna C. Larsson, Evropi Theodoratou, Xue Li.
International journal of epidemiology, 2022 [bib]

Health effects of high serum calcium levels: Updated phenome-wide Mendelian randomisation investigation and review of Mendelian randomisation studies
Shuai Yuan, Lili Yu, Wanglong Gou, Lijuan Wang, Jing Sun, Doudou Li, Ying Lu, Xiaxia Cai, Huanling Yu, Changzheng Yuan, Ju-Sheng Zheng, Susanna C. Larsson, Evropi Theodoratou, Xue Li.
EBioMedicine, 2022 [bib]

Alcohol consumption, DNA methylation and colorectal cancer risk: Results from pooled cohort studies and Mendelian randomization analysis.
Xuan Zhou, Lijuan Wang, Jiarui Xiao, Jing Sun, Lili Yu, Han Zhang, Xiangrui Meng, Shuai Yuan, Maria Timofeeva, Philip J. Law, Richard S. Houlston, Kefeng Ding, Malcolm G. Dunlop, Evropi Theodoratou, Xue Li.
International journal of cancer, 2022 [bib]

Interleukins and rheumatoid arthritis: bi-directional Mendelian randomization investigation.
Shuai Yuan, Xue Li, Ang Lin, Susanna C. Larsson.
Seminars in arthritis and rheumatism, 2022 [bib]

2021

Phenome-wide association study (PheWAS) of colorectal cancer risk SNP effects on health outcomes in UK Biobank.
Xiaomeng Zhang, Xue Li, Yazhou He, Philip J. Law, Susan M. Farrington, Harry Campbell, Ian P. Tomlinson, Richard S. Houlston, Malcolm G. Dunlop, Maria Timofeeva, Evropi Theodoratou.
British journal of cancer, 2021 [bib]

Association Between Inflammatory Bowel Disease and Dementia: A Longitudinal Cohort Study.
Yuhao Sun, Jiawei Geng, Xuejie Chen, Hui Chen, Xiaoyan Wang, Jie Chen, Xue Li, Therese Hesketh.
Inflammatory bowel diseases, 2021 [bib]

Effectiveness of public health measures in reducing the incidence of covid-19, SARS-CoV-2 transmission, and covid-19 mortality: systematic review and meta-analysis.
Stella Talic, Shivangi Shah, Holly Wild, Danijela Gasevic, Ashika Maharaj, Zanfina Ademi, Xue Li, Wei Xu, Ines Mesa-Eguiagaray, Jasmin Rostron, Evropi Theodoratou, Xiaomeng Zhang, Ashmika Motee, Danny Liew, Dragan Ilic
British Medical Journal, 2021 [bib]

An observational and Mendelian randomisation study on vitamin D and COVID-19 risk in UK Biobank.
Xue Li, Jos van Geffen, Michiel van Weele, Xiaomeng Zhang, Yazhou He, Xiangrui Meng, Maria Timofeeva, Harry Campbell, Malcolm G. Dunlop, Lina Zgaga, Evropi Theodoratou
Scientific reports, 2021 [bib]

Bi‐directional Mendelian randomisation analysis of the relationship between circulating vitamin D concentration and colorectal cancer risk.
Yazhou He, Xiaomeng Zhang, Maria Timofeeva, Susan M. Farrington, Xue Li, Wei Xu, Harry Campbell, Richard S. Houlston, Ian P. Tomlinson, Evropi Theodoratou, Malcolm G. Dunlop.
International journal of cancer, 2021 [bib]

Methodology in phenome-wide association studies: A systematic review
Lijuan Wang, Xiaomeng Zhang, Xiangrui Meng, Fotios Koskeridis, Andrea Georgiou, Lili Yu, Harry Campbell, Evropi Theodoratou, Xue Li.
Journal of medical genetics, 2021 [bib]

Aspirin Use and Common Cancer Risk: A Meta-Analysis of Cohort Studies and Randomized Controlled Trials
Lijuan Wang, Rongqi Zhang, Lili Yu, Jiarui Xiao, Xuan Zhou, Xinxuan Li, Peige Song, Xue Li.
Frontiers in oncology, 2021 [bib]

SARS-CoV-2 transmission in schools: An updated living systematic review (version 2; November 2020).
Wei Xu, Xue Li, Yijia Dong, Marshall Dozier, Yazhou He, Amir Kirolos, Zhongyu Lang, Catherine Mathews, Nandi Siegfried, Evropi Theodoratou.
Journal of global health, 2021 [bib]

Genetically Downregulated Interleukin-6 Signaling Is Associated With a Favorable Cardiometabolic Profile: A Phenome-Wide Association Study.
Marios K. Georgakis, Rainer Malik, Xue Li, Dipender Gill, Michael G. Levin, Ha My T. Vy, Renae Judy, Marylyn Ritchie, Shefali S. Verma, Regeneron Genetics Center; Girish N. Nadkarni, Scott M. Damrauer, Evropi Theodoratou, Martin Dichgans.
Circulation, 2021 [bib]

Metformin and health outcomes: An umbrella review of systematic reviews with meta-analyses.
Xue Li, Stefano Celotto, Damiano Pizzol, Danijela Gasevic, Meng-Meng Ji, Tommaso Barnini, Marco Solmi, Brendon Stubbs, Lee Smith, Guillermo F. López Sánchez, Gabriella Pesolillo, Zengli Yu, Ioanna Tzoulaki, Evropi Theodoratou, John P. A. Ioannidis, Nicola Veronese, Jacopo Demurtas.
European journal of clinical investigation, 2021 [bib]

Sarcopenia prevalence and associated factors among older Chinese population: Findings from the China Health and Retirement Longitudinal Study.
Xin Wu, Xue Li, Meihong Xu, Zhaofeng Zhang, Lixia He, Yong Li
PloS one, 2021 [bib]

The prevalence of adult attention-deficit hyperactivity disorder: A global systematic review and meta-analysis.
Peige Song, Mingming Zha, Qingwen Yang, Yan Zhang, Xue Li, Igor Rudan.
Journal of global health, 2021 [bib]

Advances in COVID-19 research until November 2020: Update from the UNCOVER registry.
Xiaomeng Zhang, Wei Xu, Marshall Dozier, Farirai P. Nzvere, Prerna Krishan, Yazhou He, Xue Li, Evropi Theodoratou.
Journal of global health, 2021 [bib]

Genetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study
Xiaomeng Zhang, Evropi Theodoratou, Xue Li, Susan M. Farrington, Philip J. Law, Peter Broderick, Marion Walker, Yann C. Klimentidis, Jessica M. B. Rees, Richard S. Houlston, Ian P. M. Tomlinson, Stephen Burgess, Harry Campbell, Malcolm G. Dunlop, Maria Timofeeva.
British journal of cancer, 2021 [bib]

Associations of Dietary Inflammatory Index with Metabolic Syndrome and Its Components: A Systematic Review and Meta-Analysis
Qian Yi, Xue Li, Yazhou He, Wei Xia, Jing Shao, Zhihong Ye, Peige Song
Public Health Nutrition, 2021 [bib]

Colorectal cancer risk variants rs10161980 and rs7495132 are associated with cancer survival outcome by a recessive mode of inheritance.
Yazhou He, Maria Timofeeva, Xiaomeng Zhang, Wei Xu, Xue Li, Farhat V. N. Din, Victoria Svinti, Susan M. Farrington, Harry Campbell, Malcolm G. Dunlop, Evropi Theodoratou
International journal of cancer, 2021 [bib]

Urate, Blood Pressure, and Cardiovascular Disease: Evidence From Mendelian Randomization and Meta-Analysis of Clinical Trials.
Dipender Gill, Alan C. Cameron, Stephen Burgess, Xue Li, Daniel J. Doherty, Ville Karhunen, Azmil H. Abdul-Rahim, Martin Taylor-Rowan, Verena Zuber, Philip S. Tsao, Derek Klarin, VA Million Veteran Program; Evangelos Evangelou, Paul Elliott, Scott M. Damrauer, Terence J. Quinn, Abbas Dehghan, Evropi Theodoratou, Jesse Dawson, Ioanna Tzoulaki.
Hypertension, 2021 [bib]

2020

What is the evidence for transmission of COVID-19 by children in schools? A living systematic review.
Wei Xu, Xue Li, Marshall Dozier, Yazhou He, Amir Kirolos, Zhongyu Lang, Catherine Mathews, Nandi Siegfried, Evropi Theodoratou
Journal of global health, 2020 [bib]

Association Between Folate and Health Outcomes: An Umbrella Review of Meta-Analyses.
Yacong Bo, Yongjian Zhu, Yuchang Tao, Xue Li, Desheng Zhai, Yongjun Bu, Zhongxiao Wan, Ling Wang, Yuming Wang, Zengli Yu
Front Public Health, 2020 [bib]

Physical activity and COVID-19: an observational and Mendelian randomisation study.
Xiaomeng Zhang, Xue Li, Ziwen Sun, Yazhou He, Wei Xu, Harry Campbell, Malcolm G. Dunlop, Maria Timofeeva, Evropi Theodoratou.
Journal of global health, 2020 [bib]

The Role of Children in the Transmission of SARS-CoV2: Updated Rapid Review.
Xue Li, Wei Xu, Marshall Dozier, Yazhou He, Amir Kirolos, Zhongyu Lang, Peige Song, Evropi Theodoratou
Journal of global health, 2020 [bib]

Physical activity, BMI and COVID-19: an observational and Mendelian randomisation study.
Xiaomeng Zhang, Xue Li, Ziwen Sun, Yazhou He, Wei Xu, Harry Campbell, Malcolm G. Dunlop, Maria Timofeeva, Evropi Theodoratou.
Journal of global health, 2020 [bib]

Prediction of Colorectal Cancer Risk Based on Profiling with Common Genetic Variants.
Xue Li, Maria Timofeeva, Athina Spiliopoulou, Paul McKeigue, Yazhou He, Xiaomeng Zhang, Victoria Svinti, Harry Campbell, Richard S. Houlston, Ian P. M. Tomlinson, Susan M. Farrington, Malcolm G. Dunlop, Evropi Theodoratou.
International journal of cancer, 2020 [bib]

The role of children in transmission of SARS-CoV-2: A rapid review.
Xue Li, Wei Xu, Marshall Dozier, Yazhou He, Amir Kirolos, Evropi Theodoratou
Journal of global health, 2020 [bib]

Risk factors and risk prediction models for colorectal cancer metastasis and recurrence: an umbrella review of systematic reviews and meta-analyses of observational studies.
Wei Xu, Yazhou He, Yuming Wang, Xue Li, Jane Young, John P. A. Ioannidis, Malcolm G. Dunlop, Evropi Theodoratou.
BMC medicine, 2020 [bib]

The disease burden of childhood asthma in China: a systematic review and meta-analysis.
Xue Li, Peige Song, Yongjian Zhu, Haohao Lei, Kit Yee Chan, Harry Campbell, Evropi Theodoratou, Igor Rudan, Global Health Epidemiology Research Group (GHERG).
Journal of global health, 2020 [bib]

Non‐genetic biomarkers and colorectal cancer risk: Umbrella review and evidence triangulation.
Xiaomeng Zhang, Dipender Gill, Yazhou He, Tian Yang, Xue Li, Grace Monori, Harry Campbell, Malcolm G. Dunlop, Konstantinos K. Tsilidis, Maria Timofeeva, Evropi Theodoratou.
Cancer medicine, 2020 [bib]

A Systematic Analysis of Interactions Between Environmental Risk Factors and Genetic Variation in Susceptibility to Colorectal Cancer.
Tian Yang, Xue Li, Susan M. Farrington, Malcolm G. Dunlop, Harry Campbell, Maria Timofeeva, Evropi Theodoratou.
Cancer epidemiology, biomarkers & prevention, 2020 [bib]

2019

Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.
Zahra Montazeri, Xue Li, Christine Nyiraneza, Xiangyu Ma, Maria Timofeeva, Victoria Svinti, Xiangrui Meng, Yazhou He, Yacong Bo, Samuel Morgan, Sergi Castellví-Bel, Clara Ruiz-Ponte, Ceres Fernández-Rozadilla, Ángel Carracedo, Antoni Castells, Timothy Bishop, Daniel Buchanan, Mark A. Jenkins, Temitope O. Keku, Annika Lindblom, Fränzel J. B. van Duijnhoven, Anna Wu, Susan M. Farrington, Malcolm G. Dunlop, Harry Campbell, Evropi Theodoratou, Wei Zheng, Julian Little.
Gut, 2019 [bib]

Gene–environment interactions and colorectal cancer risk: An umbrella review of systematic reviews and meta-analyses of observational studies.
Tian Yang, Xue Li, Zahra Montazeri, Julian Little, Susan M. Farrington, John P.A. Ioannidis, Malcolm G. Dunlop, Harry Campbell, Maria Timofeeva, Evropi Theodoratou.
International journal of cancer, 2019 [bib]

Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study.
Xue Li, Xiangrui Meng, Yazhou He, Athina Spiliopoulou, Maria Timofeeva, Wei-Qi Wei, Aliya Gifford, Tian Yang, Tim Varley, Ioanna Tzoulaki, Peter Joshi, Joshua C. Denny, Paul Mckeigue, Harry Campbell, Evropi Theodoratou.
PLoS medicine, 2019 [bib]

Mapping ICD-10 and ICD-10-CM Codes to Phecodes: Workflow Development and Initial Evaluation.
Patrick Wu, Aliya Gifford, Xiangrui Meng, Xue Li, Harry Campbell, Tim Varley, Juan Zhao, Robert Carroll, Lisa Bastarache, Joshua C. Denny, Evropi Theodoratou, Wei-Qi Wei.
JMIR Medical Informatics, 2019 [bib]

Phenome-wide Mendelian-randomization study of genetically determined Vitamin D on multiple health outcomes using the UK Biobank study.
Xiangrui Meng, Xue Li, Maria Timofeeva, Yazhou He, Athina Spiliopoulou, Wei-Qi Wei, Aliya Gifford, Hongjiang Wu, Timothy Varley, Peter Joshi, Joshua C. Denny, Susan M. Farrington, Lina Zgaga, Malcolm G. Dunlop, Paul McKeigue, Harry Campbell, Evropi Theodoratou.
International journal of epidemiology, 2019 [bib]

A Comprehensive Study of the Effect on Colorectal Cancer Survival of Common Germline Genetic Variation Previously Linked with Cancer Prognosis.
Yazhou He, Maria Timofeeva, Xue Li, Farhat V.N. Din, James P. Blackmur, Peter Vaughan Shaw, Victoria Svinti, Susan M. Farrington, Harry Campbell, Malcolm G. Dunlop, Evropi Theodoratou.
Cancer epidemiology, biomarkers & prevention,, 2019 [bib]

Effects of common genetic variants associated with colorectal cancer risk on survival outcomes after diagnosis: A large population-based cohort study.
Yazhou He, Evropi Theodoratou, Xue Li, Farhat V.N. Din, Peter Vaughan Shaw, Victoria Svinti, Susan M. Farrington, Harry Campbell, Malcolm G. Dunlop, Maria Timofeeva.
International journal of cancer, 2019 [bib]

Performance of prediction models on survival outcomes of colorectal cancer with surgical resection: A systematic review and meta-analysis.
Yazhou He, Yuhan Ong, Xue Li, Farhat V.N. Din, Ewan Brown, Maria Timofeeva, Ziqiang Wang, Susan M. Farrington, Harry Campbell, Malcolm G. Dunlop, Evropi Theodoratou.
Surgical Oncology, 2019 [bib]

Temporal trends in normal weight central obesity and its associations with cardiometabolic risk among Chinese adults
Peige Song, Xue Li, Yongjun Bu, Shibin Ding, Desheng Zhai, Erhui Wang, Zengli Yu.
Scientific reports, 2019 [bib]

Global Disease Burden Estimates of Respiratory Syncytial Virus-Associated Acute Respiratory Infection in Older Adults in 2015: A Systematic Review and Meta-Analysis.
Ting Shi, Angeline Denouel, Anna K. Tietjen, Iain Campbell, Emily Moran, Xue Li, Harry Campbell, Clarisse Demont, Bryan O. Nyawanda, Helen Y. Chu, Sonia K. Stoszek, Anand Krishnan, Peter Openshaw, Ann R. Falsey, Harish Nair.
The Journal of infectious diseases, 2019 [bib]

2018

Statins and Multiple Noncardiovascular Outcomes: Umbrella Review of Meta-analyses of Observational Studies and Randomized Controlled Trials.
Yazhou He, Xue Li, Danijela Gasevic, Eleanor Brunt, Fiona McLachlan, Marisa Millenson, Maria Timofeeva, John P.A. Ioannidis, Harry Campbell, Evropi Theodoratou.
Annals of Internal Medicine, 2018 [bib]

Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk: A large Mendelian randomisation study.
Yazhou He, Maria Timofeeva, Susan M. Farrington, Peter Vaughan-Shaw, Victoria Svinti, Marion Walker, Lina Zgaga, Xiangrui Meng, Xue Li, Athina Spiliopoulou, Xia Jiang, Elina Hyppönen, Peter Kraft, Douglas P. Kiel, The SUNLIGHT consortium, Caroline Hayward, Archie Campbell, David Porteous, Katarina Vucic, Iva Kirac, Masa Filipovic, Sarah E. Harris, Ian J. Deary, Richard S. Houlston, Ian P. Tomlinson, Harry Campbell, Evropi Theodoratou, Malcolm G. Dunlop.
BMC medicine, 2018 [bib]

MR-PheWAS: exploring the causal effect of SUA level on multiple disease outcomes by using genetic instruments in UK Biobank
Xue Li, Xiangrui Meng, Athina Spiliopoulou, Maria Timofeeva, Wei-Qi Wei, Aliya Gifford, Xia Shen, Yazhou He, Tim Varley, Paul McKeigue, Ioanna Tzoulaki, Alan F. Wright, Peter Joshi, Joshua C. Denny, Harry Campbell, Evropi Theodoratou.
Annals of the rheumatic diseases, 2018 [bib]

2017

Prevalence of chronic obstructive pulmonary disease (COPD) in China in 1990 and 2010.
Kit Yee Chan, Xue Li, Wanjing Chen, Peige Song, Nuen Wing Katy Wong, Adrienne N. Poon, Wenyan Jian, Ireneous Y. Soyiri, Simon Cousens, Davies Adeloye, Aziz Sheikh, Harry Campbell, Igor Rudan, Global Health Epidemiology Research Group (GHERG).
Journal of global health, 2017 [bib]

Nature, Nurture, and Cancer Risks: Genetic and Nutritional Contributions to Cancer.
Evropi Theodoratou, Maria Timofeeva, Xue Li, Xiangrui Meng, John P.A. Ioannidis.
Annual review of nutrition, 2017 [bib]

Serum uric acid levels and multiple health outcomes: Umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian randomisation studies.
Xue Li, Xiangrui Meng, Maria Timofeeva, Ioanna Tzoulaki, Konstantinos K. Tsilidis, John P. A. Ioannidis, Harry Campbell, Evropi Theodoratou.
British Medical Journal, 2017 [bib]

The Disease Burden and Clinical Characteristics of Inflammatory Bowel Disease in the Chinese Population: A Systematic Review and Meta-Analysis.
Xue Li, Peige Song, Jun Li, Yuchang Tao, Guowei Li, Xiumin Li, Zengli Yu.
International journal of environmental research and public health, 2017 [bib]